Junhong ChenUniversity of Wisconsin Milwaukee, USA
Dr. Chen is currently a Distinguished Professor of Mechanical Engineering and Materials Science and engineering and Excellence in Engineering Faculty Fellow in Nanotechnology at the University of Wisconsin-Milwaukee (UWM). He is also the Director of NSF I/UCRC on Water Equipment & Policy and the founder of NanoAffix Science, LLC. Dr. Chen received his B.E. degree (in Thermal Engineering) in 1995 from Tongji University, and his M.S. and Ph.D. degrees (both in Mechanical Engineering) in 2000 and 2002, respectively, from University of Minnesota. Prior to joining UWM in 2003, he was a postdoctoral scholar in Chemical Engineering at California Institute of Technology. He was promoted to Associate Professor and Professor in 2008 and 2011, respectively. His current research focuses on nanocarbon-based hybrid nanomaterials for sustainable energy and environment. His research excellence was recognized by the 2008 Graduate School/UWM Foundation Research Award, the 2012 UWM College of Engineering & Applied Science Research Excellence Award, the 2014 UWM Research Foundation Senior Faculty Research Award, an elected Fellow of American Society of Mechanical Engineers (ASME) in 2013, and the 2015 Inaugural Regent Scholar of UW System.
Title：Graphene-based Nanomaterials for Versatile Biosensors
SymposiumB03 Bio-sensors
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Abstract
As a representative two-dimensional (2D) nanomaterial, graphene has attracted significant attention in the field of ultrasensitive sensors because of its excellent electronic and chemical properties, and large specific surface area. In this talk, three different types of graphene-based materials with unique features, i.e., reduced graphene oxide (rGO), crumpled graphene (CG), and vertically-oriented graphene (VG), will be introduced, together with their applications for versatile biosensors based on two major biosensing mechanisms (electronic sensing and electrochemical sensing). In an electronic biosensor, graphene-based materials are functionalized with gold nanoparticle (NP)-antibody conjugates and used as a conducting channel in a field-effect transistor (FET). Electrical detection of protein binding is accomplished through FET and direct current (dc) measurements. In an electrochemical biosensor, highly electrocatalytic metal oxides are combined with graphene-based materials to offer both a high electrocatalytic activity and a high electrical conductivity for enzymeless biosensing. Biomolecules are then detected through electrochemical measurements such as cyclic voltammetry. The above-mentioned graphene-based platforms will be demonstrated for the detection of Escherichia coli (E. coli) bacteria, glucose, and various proteins.
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